Ka litlolo tsa tlhaho, tse tala, tse phetseng hantle le tse sireletsehileng tse nang le lihlahisoa tsa limela tse hohelang tlhokomelo e eketsehileng, nts'etsopele ea lintho tse sebetsang tse tsoang mehloling ea limela le nts'etsopele ea litlolo tse hloekileng tsa tlhaho li fetohile tse ling tsa lihlooho tse sebetsang ka ho fetisisa ho nts'etsopele ea indasteri ea litlolo. Ho tsosolosa lisebelisoa tsa limela hase feela ho tsosolosa histori, empa ho tšehetsa setso sa setso sa Machaena, ho kopanya likhopolo tsa setso tsa meriana ea setso ea Machaena, le ho sebelisa theknoloji ea morao-rao ea biochemical ho hlahisa mefuta e mecha ea litlolo tse entsoeng ke limela, e le ho ntlafatsa saense le polokeho. litlolo tsa tlhaho. Lihlahisoa tsa lik'hemik'hale li fana ka lisebelisoa tse tala tse tala. Ho feta moo, lihlahisoa tsa limela li sebelisoa haholo meriana, li-supplement tsa lijo, lijo tse sebetsang hantle, lino, litlolo, litlolo le masimo a mang.
Metsoako ea Semela(PE) e bua ka limela tse nang le limolek'hule tse nyane tsa baeloji le limolek'hule tse kholo joalo ka 'mele o ka sehloohong o entsoeng ka morero oa ho arola le ho hloekisa motsoako o le mong kapa tse ling tse sebetsang lihlahisoa tsa limela ka mekhoa ea 'mele, ea lik'hemik'hale le ea tlhaho. Litlolo tse entsoeng ka lihlahisoa tsa limela e le lisebelisoa tse sebetsang li na le melemo e mengata ha li bapisoa le litlolo tsa setso: li hlōla mefokolo ea litlolo tsa setso tse itšetlehileng ka lik'hemik'hale tsa lik'hemik'hale, ho etsa hore sehlahisoa se sireletsehe; likarolo tsa tlhaho li kenngoa habonolo ke letlalo, li etsa hore sehlahisoa se atlehe haholoanyane 'me phello e be ea bohlokoa haholoanyane; mosebetsi o hlahelletse ho feta, joalo-joalo.
Ho khetha sehlahisoa se nepahetseng sa semela le ho eketsa palo e nepahetseng ea semela ho lihlahisoa tsa litlolo ho ka eketsa phello ea sona. Mesebetsi e ka sehloohong ea lihlahisoa tsa limela ka litlolo ke: ho nosetsa, ho thibela botsofali, ho tlosoa ha li-freckle, tšireletso ea letsatsi, li-antiseptic, joalo-joalo, le lihlahisoa tsa limela li tala ebile li bolokehile.
Mphello ea oisturizing
Thepa ea moisturizing ka litlolo haholo-holo e etsoa ka litsela tse peli: e 'ngoe e finyelloa ke phello ea ho koala metsi ea ho etsa maqhama a hydrogen pakeng tsa moemeli oa moisturizing le limolek'hule tsa metsi; e 'ngoe ke hore oli e etsa filimi e koetsoeng holim'a letlalo.
Seo ho thoeng ke litlolo tse nang le mongobo ke litlolo tse nang le metsoako ea mongobo ho boloka mongobo oa stratum corneum ho tsosolosa khanya le elasticity ea letlalo. Litlolo tse nang le mongobo li arotsoe haholo ka mefuta e 'meli ho ea ka litšobotsi tsa tsona: e' ngoe ke ho sebelisa lintho tse bolokang metsi tse ka kopanngoang ka matla le mongobo holim'a letlalo ho nosetsa stratum corneum, e bitsoang li-moisturizing agents, tse kang glycerin; e 'ngoe ke ntho e ke keng ea qhibiliha ka metsing, Lera la filimi ea lubricating le thehoa holim'a letlalo, le sebetsang e le tiiso ho thibela tahlehelo ea metsi, e le hore stratum corneum e boloke mongobo o itseng, o bitsoang emollients kapa li-conditioner, tse kang petrolatum, oli, le boka.
Ho na le limela tse 'maloa semeleng tse nang le phello ea hydrating le moisturizing, joalo ka lekhala vera, seaweed, mohloaare, chamomile, joalo-joalo, kaofela li na le phello e ntle ea mongobo.
Phello e khahlanong le botsofali
Ka keketseho ea lilemo, letlalo le qala ho bontša boemo ba botsofali, bo kenyelletsang haholo-holo ho fokotseha ha collagen, elastin, mucopolysaccharide le lintho tse ling tse ka har'a letlalo ho ea ka likhato tse sa tšoaneng, methapo ea mali e fanang ka letlalo la phepo ea letlalo atrophy, elasticity ea methapo ea mali. lebota le fokotseha, 'me letlalo la epidermis le fokotseha butle-butle. Ho ruruha, ho fokotsa mafura a subcutaneous, le ponahalo ea wrinkles, chloasma le matheba a lilemo.
Hajoale, liphuputso tse fetileng mabapi le lisosa tsa botsofali ba batho li akaretsa lintlha tse latelang:
E 'ngoe ke ho eketseha le ho tsofala ha li-radicals tsa mahala. Li-radicals tsa mahala ke liathomo kapa limolek'hule tse nang le li-electrone tse sa sebetseng tse hlahisoang ke homolysis ea li-covalent bonds. Ba na le tekanyo e phahameng ea ts'ebetso ea lik'hemik'hale 'me ba fetile peroxidation ka lipids tse sa tsitsang. Lipid peroxide (LPO), le sehlahisoa sa eona sa ho qetela, malondialdehyde (MDA), e ka sebetsana le lintho tse ngata liseleng tse phelang, e leng se etsang hore biofilm e fokotsehe, ho senyeha ha limolek'hule tsa DNA, le lefu la lisele kapa phetoho ea phetoho .
Ea bobeli, mahlaseli a UVB le a UVA ha a le khanyeng ea letsatsi a ka etsa hore letlalo le chese. Mahlaseli a ultraviolet haholo-holo a baka botsofali ba letlalo ka mekhoa e latelang: 1) tšenyo ea DNA; 2) ho hokahanya ha collagen; 3) ho fokotseha ha karabelo ea 'mele ea ho itšireletsa mafung ka ho etsa hore ho be le tsela e thibelang likokoana-hloko ea karabelo ea antigen-stimulated; 4) moloko oa li-radicals tsa mahala tse sebetsang haholo tse sebetsanang le mekhoa e sa tšoaneng ea intracellular 5. Ho thibela ka ho toba mosebetsi oa lisele tsa epidermal Langerhans, ho baka photoimmunosuppression le ho fokolisa ts'ebetso ea 'mele ea ho itšireletsa mafung ea letlalo. Ho feta moo, glycosylation e seng enzymatic, mathata a metabolism, le botsofali ba matrix metalloproteinase le tsona li tla ama botsofali ba letlalo.
Li-extracts tsa limela e le li-inhibitors tsa tlhaho tsa elastase e bile taba e chesang ea lipatlisiso lilemong tsa morao tjena, joalo ka Scutellaria baikalensis, Burnet, peo ea Morinda citrifolia, Moringa, Shuihe, Forsythia, Salvia, Angelica joalo-joalo. Liphello tsa thuto li bontša hore: Salvia miltiorrhiza extract (ESM) e ka susumetsa polelo ea filaggrin ka keratinocyte e tloaelehileng ea motho le AmoRe Skin, e leng eona e ka ntlafatsang mosebetsi oa ho khetholla ha epidermal le hydration, le ho bapala karolo ea ho hanela botsofali le ho nosetsa. ; ho tsoa limeleng tse jeoang Ntša DPPH e sebetsang hantle ea anti-free radical, 'me u e sebelise ho lihlahisoa tse loketseng tsa litlolo, ka liphello tse ntle; Polygonum cuspidatum e na le phello e itseng ea thibelo ho elastase, kahoo e thibela ho tsofala le ho thibela wrinkles.
Freckle
Phapang ea 'mala oa letlalo oa' mele oa motho hangata e ipapisitse le litaba le kabo ea epidermal melanin, phallo ea mali ea dermis, le botenya ba stratum corneum. Ho fifala ha letlalo kapa ho thehoa ha matheba a lefifi ho angoa haholo ke ho bokellana ha melanin e ngata, letlalo la oxidation, keratinocyte deposition, microcirculation ea letlalo, le ho bokella chefo 'meleng.
Matsatsing ana, phello ea ho tlosoa ha li-freckle e finyelloa haholo-holo ka ho ama sebopeho le ho ata ha melanin. E 'ngoe ea tsona ke tyrosinase inhibitor. Phetohong ho tloha ho tyrosine ho ea ho dopa le dopa ho ea dopaquinone, ka bobeli li hlahisoa ke tyrosinase, e laolang ka kotloloho ho qalisoa le lebelo la motsoako oa melanin, mme e etsa qeto ea hore na mehato e latelang e ka tsoela pele.
Ha lintlha tse fapaneng li sebetsa ho tyrosinase ho eketsa ts'ebetso ea eona, motsoako oa melanin oa eketseha, 'me ha mosebetsi oa tyrosinase o thibetsoe, motsoako oa melanin oa fokotseha. Liphuputso li bontšitse hore arbutin e ka thibela ts'ebetso ea tyrosinase sebakeng sa mahloriso ntle le chefo ea melanocyte, ea thibela tlhahiso ea dopa, kahoo e thibela tlhahiso ea melanin. Bafuputsi ba ithutile likarolo tsa lik'hemik'hale tsa li-rhizome tsa nkoe e ntšo le litlamorao tsa tsona tse tšoeu, ha ba ntse ba hlahloba ho teneha ha letlalo.
Liphello tsa lipatlisiso li bontša hore: har'a metsoako ea 17 e arohaneng (HLH-1～17), HLH-3 e ka thibela ho thehoa ha melanin, e le ho finyella phello ea ho soeufala, 'me motsoako o na le bohale bo tlaase haholo ho letlalo. Ren Hongrong et al. li pakile ka liteko hore motsoako oa joala oa perfume lotus o na le phello e kholo ea thibelo ho thehoeng ha melanin. Joalo ka mofuta o mocha oa bosoeu bo entsoeng ke semela, bo ka tsoakoa ka har'a setlolo se loketseng 'me se ka etsoa ho hlokomela letlalo, ho thibela botsofali le ho tlosa matheba. Litlolo tse sebetsang.
Hape ho na le moemeli oa melanocyte cytotoxic, joalo ka li-endothelin antagonists tse fumanoang lihlahisoa tsa limela, tse ka thibelang ka tlhōlisano ho tlamaha ha endothelin ho melanocyte membrane receptors, ho thibela ho arohana le ho ata ha melanocyte, e le ho thibela mahlaseli a kotsi a Ultraviolet a susumetsa morero oa melanin. tlhahiso. Ka liteko tsa lisele, Frédéric Bonté et al. e bontšitse hore motsoako o mocha oa orchid oa Brassocattleya o ka thibela ka katleho ho ata ha melanocyte. Ho e kenyelletsa ho litlolo tse loketseng tsa litlolo ho na le liphello tse totobetseng tsa ho soeufala ha letlalo le ho khanya. Zhang Mu et al. e ntšitsoeng le ho ithuta lihlahisoa tsa litlama tsa Sechaena tse kang Scutellaria baicalensis, Polygonum cuspidatum le Burnet, 'me liphello li bontšitse hore li-extracts tsa bona li ka thibela ho ata ha lisele ho ea ka likhato tse sa tšoaneng, li thibela haholo mosebetsi oa intracellular tyrosinase,' me li fokotsa haholo melanin ea intracellular, e le hore e finyelloe. phello ya bosweu ba matheba.
tshireletso letsatsing
Ka kakaretso, litlolo tse sireletsang letlalo letsatsing tse atisang ho sebelisoa litlolong tse sireletsang letlalo letsatsing li arotsoe ka lihlopha tse peli: se seng ke metsoako ea lintho tse phelang, tse kang ketone; e 'ngoe ke lisebelisoa tse sireletsang UV, ke hore, li-sunscreens tsa 'mele, tse kang TiO2, ZnO. Empa mefuta ena e ’meli ea litlolo tse sireletsang letlalo letsatsing e ka baka ho teneha ha letlalo, ho hanana le letlalo, le masoba a koalehileng a letlalo. Leha ho le joalo, limela tse ngata tsa tlhaho li na le phello e ntle ea ho monya mahlaseli a ultraviolet, 'me ka tsela e sa tobang li matlafatsa ts'ebetso ea lihlahisoa tse sireletsang letsatsi ka ho fokotsa tšenyo e bakoang ke mahlaseli a ultraviolet letlalong.
Ho phaella moo, metsoako e sireletsang letsatsi ka lihlahisoa tsa limela e na le melemo ea ho fokotsa letlalo la letlalo, botsitso ba photochemical, polokeho le botšepehi ha li bapisoa le li-sunscreens tsa setso le tsa 'mele. Zheng Hongyan et al. e khethileng li-extracts tse tharo tsa limela tsa tlhaho, cortex, resveratrol le arbutin, 'me e ithutile polokeho le litlamorao tsa ts'ireletso ea UVB le UVA ea litlolo tsa bona tse kopaneng tsa setlolo sa letsatsi ka liteko tsa batho. Liphetho tsa lipatlisiso li bonts'a hore: lihlahisoa tse ling tsa limela tsa tlhaho li bonts'a phello e ntle ea ts'ireletso ea UV. Tataiso le ba bang ba sebelisitse li-flavonoids tsa tartar buckwheat e le lisebelisoa tse tala ho ithuta ka thepa e sireletsang letsatsi ea flavonoids. Phuputso e fumane hore tšebeliso ea li-flavonoids ho li-emulsion tsa sebele le ho kopanya le li-sunscreens tsa 'mele le tsa lik'hemik'hale li fane ka motheo oa khopolo ea ho sebelisoa ha limela tsa letsatsi ka litlolo nakong e tlang.
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Aterese: YA AN temo HI-tech Ecological park, Ya'an City, Sichuan China 625000
Nako ea poso: Jul-12-2022