Berberine, kapa berberine hydrochloride, ke motsoako o fumanoang limela tse ngata.E ka thusa ho phekola maemo a kang lefu la tsoekere, k'holeseterole e phahameng le khatello e phahameng ea mali.Leha ho le joalo, litla-morao li ka kenyelletsa ho ferekana ka mpeng le ho nyekeloa ke pelo.
Berberine esale e le karolo ea meriana ea setso ea Machaena le Ayurvedic ka lilemo tse likete.E sebetsa 'meleng ka litsela tse fapaneng' me e khona ho baka liphetoho ka har'a lisele tsa 'mele.
Patlisiso ka berberine e fana ka maikutlo a hore e ka phekola mafu a fapaneng a metabolism, ho kenyelletsa lefu la tsoekere, botenya le lefu la pelo.E ka boela ea ntlafatsa bophelo bo botle ba mala.
Le hoja berberine e bonahala e sireletsehile ebile e na le litla-morao tse fokolang, u lokela ho buisana le ngaka ea hau pele u e nka.
Berberine e ka ba moemeli ea sebetsang oa antibacterial.Phuputso ea 2022 e fumane hore berberine e thusa ho thibela kholo ea Staphylococcus aureus.
Phuputso e 'ngoe e fumane hore berberine e ka senya DNA le liprotheine tsa libaktheria tse ling.
Lipatlisiso li bontša hore berberine e na le thepa e khahlanong le ho ruruha, ho bolelang hore e ka thusa ho phekola lefu la tsoekere le mafu a mang a amanang le ho ruruha.
Lipatlisiso li fana ka maikutlo a hore berberine e ka ba molemo ho alafa lefu la tsoekere.Lipatlisiso li bontšitse hore e ka ba le phello e ntle ho:
Tlhahlobo e tšoanang e fumane hore motsoako oa berberine le moriana o theolang tsoekere maling o ne o sebetsa ho feta sethethefatsi se le seng.
Ho ea ka phuputso ea 2014, berberine e bontša tšepiso e le phekolo e ka 'nang ea e-ba teng bakeng sa lefu la tsoekere, haholo-holo ho batho ba sa khoneng ho noa lithethefatsi tse teng tsa antidiabetic ka lebaka la lefu la pelo, ho hloleha ha sebete kapa mathata a liphio.
Tlhahlobo e 'ngoe ea lingoliloeng e fumane hore berberine e kopantsoeng le liphetoho tsa bophelo bo fokolitse tsoekere ea mali ho feta liphetoho tsa bophelo feela.
Ho bonahala eka Berberine e kenya AMP-activated protein kinase, e thusang ho laola tšebeliso ea 'mele ea tsoekere e maling.Bafuputsi ba lumela hore ts'ebetso ena e ka thusa ho phekola lefu la tsoekere le mathata a amanang le bophelo bo botle joalo ka botenya le k'holeseterole e phahameng.
Tlhahlobo e 'ngoe ea meta e entsoeng ka 2020 e bonts'itse ntlafatso ea boima ba' mele le litekanyetso tsa metabolic ntle le keketseho e kholo ea maemo a enzyme ea sebete.
Leha ho le joalo, bo-ramahlale ba hloka ho etsa lithuto tse kholoanyane, tse foufetseng habeli ho tseba ka botlalo polokeho le katleho ea berberine.
Bua le ngaka ea hau pele u nka berberine bakeng sa lefu la tsoekere.E ka 'na ea se ke ea tšoanela bohle' me e ka sebelisana le meriana e meng.
Maemo a phahameng a k’holeseterole le low-density lipoprotein (LDL) triglycerides a ka eketsa kotsi ea lefu la pelo le stroke.
Bopaki bo bong bo fana ka maikutlo a hore berberine e ka thusa ho theola cholesterol ea LDL le triglycerides.Ho ea ka tlhahlobo e 'ngoe, lithuto tsa liphoofolo le batho li bontša hore berberine e theola k'holeseterole.
Sena se ka thusa ho theola LDL, k'holeseterole e "mpe", le ho eketsa HDL, "cholesterol" e ntle.
Tlhahlobo ea lingoliloeng e fumane hore berberine e kopantsoeng le liphetoho tsa mokhoa oa bophelo e sebetsa haholo ho phekola k'holeseterole e phahameng ho feta ho fetola mokhoa oa bophelo feela.
Bafuputsi ba lumela hore berberine e ka sebetsa ka mokhoa o ts'oanang le lithethefatsi tse theolang cholesterol ntle le ho baka litlamorao tse tšoanang.
Tlhahlobo ea lingoliloeng e fumane hore berberine e ne e sebetsa haholo hammoho le lithethefatsi tse fokotsang khatello ea mali ho feta ka boeona.
Ho feta moo, liphetho tsa liphuputso tsa likhoto li bontša hore berberine e ka liehisa ho qala ha khatello e phahameng ea mali mme ea thusa ho fokotsa matla a eona ha khatello e phahameng ea mali e etsahala.
Tlhahlobo e 'ngoe e tlalehile tahlehelo e kholo ea boima ba' mele ho batho ba nkang 750 milligrams (mg) ea barberry habeli ka letsatsi bakeng sa likhoeli tse 3.Barberry ke semela se nang le berberine e ngata.
Ho feta moo, boithuto bo sa boneng habeli bo fumane hore batho ba nang le metabolic syndrome ba neng ba nka 200 mg ea barberry hararo ka letsatsi ba na le index e tlase ea boima ba 'mele.
Sehlopha se entseng boithuto bo bong se hlokometse hore berberine e ka kenya tšebetsong lisele tse sootho tsa adipose.Tishu ena e thusa 'mele ho fetolela lijo hore e be mocheso oa' mele, 'me ts'ebetso e eketsehileng e ka thusa ho phekola botenya le metabolic syndrome.
Liphuputso tse ling li fana ka maikutlo a hore berberine e sebetsa ka tsela e tšoanang le ea metformin, eo hangata lingaka li e laelang ho phekola lefu la tsoekere la mofuta oa 2.Ebile, berberine e kanna ea ba le bokhoni ba ho fetola libaktheria tsa mala, tse ka thusang ho phekola botenya le lefu la tsoekere.
Polycystic ovary syndrome (PCOS) e etsahala ha basali ba e-na le litekanyetso tse phahameng tsa lihomone tse itseng tsa banna.Lefu lena ke ho se leka-lekane ha li-hormone le metabolism e ka lebisang ho hloka thari le mathata a mang a bophelo bo botle.
Polycystic ovary syndrome e amahanngoa le mathata a mangata ao berberine e ka thusang ho a rarolla.Mohlala, batho ba nang le PCOS le bona ba ka ba le:
Ka linako tse ling lingaka li fana ka metformin, moriana oa lefu la tsoekere, ho phekola PCOS.Kaha berberine e na le litlamorao tse ts'oanang le metformin, e kanna ea ba khetho e ntle ea kalafo bakeng sa PCOS.
Tlhahlobo e hlophisitsoeng e fumane hore berberine e na le ts'episo kalafong ea lefu la polycystic ovary le ho hanyetsa insulin.Leha ho le joalo, bangoli ba hlokomela hore netefatso ea litlamorao tsena e hloka lipatlisiso tse ling.
Berberine e ka baka liphetoho ho limolek'hule tsa cellular, tse ka bang le molemo o mong hape: ho loantša mofetše.
Phuputso e 'ngoe e fana ka maikutlo a hore berberine e thusa ho phekola mofetše ka ho thibela tsoelo-pele ea eona le potoloho ea bophelo bo tloaelehileng.E ka boela ea phetha karolo ea ho bolaea lisele tsa mofetše.
Ho latela lintlha tsena, bangoli ba bolela hore berberine ke "sethethefatsi se sebetsang hantle haholo, se bolokehileng le se theko e tlaase" sa anticancer.
Leha ho le joalo, ho bohlokoa ho hopola hore bafuputsi ba ithutile feela litlamorao tsa berberine liseleng tsa mofetše ka laboratoring eseng ho batho.
Ho latela lithuto tse ling tse phatlalalitsoeng ka 2020, haeba berberine e ka thusa ho phekola mofetše, ho ruruha, lefu la tsoekere le mafu a mang, e kanna ea ba ka lebaka la litlamorao tsa eona ho microbiome ea mala.Bo-rasaense ba fumane kamano pakeng tsa gut microbiome (likolone tsa libaktheria ka maleng) le maemo ana.
Berberine e na le thepa e thibelang likokoana-hloko 'me e bonahala e tlosa libaktheria tse kotsi ka maleng, kahoo e khothalletsa kholo ea libaktheria tse phetseng hantle.
Leha liphuputso ho batho le litoeba li fana ka maikutlo a hore sena e kanna ea ba 'nete, bo-rasaense ba hlokomelisa hore lipatlisiso tse ling lia hlokahala ho netefatsa hore na berberine e ama batho joang le hore na e bolokehile ho e sebelisa.
Mokhatlo oa Amerika oa Lingaka tsa Naturopathic (AANP) o bolela hore li-supplement tsa berberine li fumaneha ka foromo ea tlatsetso kapa ea capsule.
Ba phaella ka hore lithuto tse ngata li khothalletsa ho nka 900-1500 mg ka letsatsi, empa batho ba bangata ba nka 500 mg ka makhetlo a mararo ka letsatsi.Leha ho le joalo, AANP e khothalletsa batho hore ba buisane le ngaka pele ba nka berberine ho hlahloba hore na e bolokehile ho e sebelisa le hore na e ka nooa ka tekanyo efe.
Haeba ngaka e lumela hore berberine e bolokehile hore e ka sebelisoa, batho ba lokela ho hlahloba leibole ea sehlahisoa bakeng sa setifikeiti sa motho oa boraro, joalo ka National Science Foundation (NSF) kapa NSF International, ho bolela AANP.
Bangoli ba phuputso ea 2018 ba fumane hore litaba tsa li-capsules tse fapaneng tsa berberine li fapane haholo, tse ka bakang pherekano mabapi le polokeho le litekanyetso.Ha baa ka ba fumana hore litšenyehelo tse phahameng li ne li hlile li bontša boleng bo phahameng ba sehlahisoa.
US Food and Drug Administration (FDA) ha e laole li-supplement tsa lijo.Ha ho na tiiso ea hore li-supplement li bolokehile kapa li sebetsa hantle, 'me ha se kamehla ho ka khonehang ho netefatsa boleng ba sehlahisoa.
Bo-rasaense ba re berberine le metformin li na le litšobotsi tse ngata 'me ka bobeli li ka thusa ho alafa lefu la tsoekere la mofuta oa 2.
Leha ho le joalo, haeba ngaka e laela motho metformin, ha baa lokela ho nka berberine e le mokhoa o mong ntle le hore ba buisane le ngaka ea bona pele.
Lingaka li tla fana ka tekanyetso e nepahetseng ea metformin bakeng sa motho ho latela lithuto tsa kliniki.Ha ho khonehe ho tseba hore na li-supplement li lumellana hantle hakae le palo ena.
Berberine e ka sebelisana le metformin mme ea ama tsoekere ea mali, e etsa hore ho be thata ho e laola.Phuputsong e 'ngoe, ho nka berberine le metformin hammoho ho fokolitse litlamorao tsa metformin ka 25%.
Berberine ka letsatsi le leng e kanna ea ba mokhoa o mong o loketseng ho fapana le metformin bakeng sa taolo ea tsoekere ea mali, empa lipatlisiso tse ling lia hlokahala.
Setsi sa Sechaba sa Bophelo bo Botle ba Tlatsetso le bo Kopanetsoeng (NCCIH) se bolela hore goldenrod, e nang le berberine, ha ho bonolo ho baka litla-morao tse tebileng ka nako e khutšoanyane haeba batho ba baholo ba e nka ka molomo.Leha ho le joalo, ha ho na tlhahisoleseding e lekaneng ho bontša hore e bolokehile bakeng sa tšebeliso ea nako e telele.
Lithutong tsa liphoofolo, bo-rasaense ba hlokometse litlamorao tse latelang ho latela mofuta oa phoofolo, palo le nako ea tsamaiso:
Ke habohlokoa ho buisana le ngaka ea hau pele u noa berberine kapa lisebelisoa tse ling kaha li ka 'na tsa se ke tsa sireletseha' me li ka 'na tsa se ke tsa tšoanela motho e mong le e mong.Mang kapa mang ea nang le bothata ba ho hanyetsa sehlahisoa leha e le sefe sa litlama o lokela ho khaotsa ho se sebelisa hang-hang.
Nako ea poso: Dec-07-2023
